BDBM50399761 CHEMBL2179833

SMILES: [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O

InChI Key: InChIKey=DYZQGMRMIGDHBE-YFWBWJTRSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399761 (CHEMBL2179833) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O |r| Show InChI InChI=1S/C57H110N16O9/c1-34(2)30-43(64-27-19-15-13-12-14-16-22-39(11)74)51(78)70-45(32-36(5)6)53(80)72-46(33-37(7)8)54(81)71-44(31-35(3)4)52(79)68-42(25-21-29-66-57(62)63)50(77)73-47(38(9)10)55(82)69-41(23-17-18-26-58)49(76)67-40(48(59)75)24-20-28-65-56(60)61/h34-38,40-47,64H,12-33,58H2,1-11H3,(H2,59,75)(H,67,76)(H,68,79)(H,69,82)(H,70,78)(H,71,81)(H,72,80)(H,73,77)(H4,60,61,65)(H4,62,63,66)/t40-,41-,42-,43-,44-,45-,46-,47-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA (Homo sapiens (Human))	BDBM50399761 (CHEMBL2179833) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O |r| Show InChI InChI=1S/C57H110N16O9/c1-34(2)30-43(64-27-19-15-13-12-14-16-22-39(11)74)51(78)70-45(32-36(5)6)53(80)72-46(33-37(7)8)54(81)71-44(31-35(3)4)52(79)68-42(25-21-29-66-57(62)63)50(77)73-47(38(9)10)55(82)69-41(23-17-18-26-58)49(76)67-40(48(59)75)24-20-28-65-56(60)61/h34-38,40-47,64H,12-33,58H2,1-11H3,(H2,59,75)(H,67,76)(H,68,79)(H,69,82)(H,70,78)(H,71,81)(H,72,80)(H,73,77)(H4,60,61,65)(H4,62,63,66)/t40-,41-,42-,43-,44-,45-,46-,47-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant furin expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair