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SMILES: CCCOc1ccc(cc1-c1nc(C)cc(=O)[nH]1)S(=O)(=O)N1CCN(C)CC1

InChI Key: InChIKey=KXGOMGJXIMPGGC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50399905
PNG
(CHEMBL2180657)
Show SMILES CCCOc1ccc(cc1-c1nc(C)cc(=O)[nH]1)S(=O)(=O)N1CCN(C)CC1
Show InChI InChI=1S/C19H26N4O4S/c1-4-11-27-17-6-5-15(28(25,26)23-9-7-22(3)8-10-23)13-16(17)19-20-14(2)12-18(24)21-19/h5-6,12-13H,4,7-11H2,1-3H3,(H,20,21,24)
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MMDB

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Similars
Article
PubMed
n/an/a 71n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assay

J Med Chem 55: 10540-50 (2012)


Article DOI: 10.1021/jm301159y
BindingDB Entry DOI: 10.7270/Q2154J6G
More data for this
Ligand-Target Pair