BDBM50399927 CHEMBL2180988

SMILES: CS(=O)(=O)Nc1ccc2[nH]cc(C(=O)CN3CCC(Cc4ccccc4)CC3)c2c1

InChI Key: InChIKey=CHYLBWWOFBNLRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50399927 (CHEMBL2180988) Show SMILES CS(=O)(=O)Nc1ccc2[nH]cc(C(=O)CN3CCC(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C23H27N3O3S/c1-30(28,29)25-19-7-8-22-20(14-19)21(15-24-22)23(27)16-26-11-9-18(10-12-26)13-17-5-3-2-4-6-17/h2-8,14-15,18,24-25H,9-13,16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortex after 120 mins				J Med Chem 55: 10532-9 (2012) Article DOI: 10.1021/jm301508d BindingDB Entry DOI: 10.7270/Q2RN3919
					More data for this Ligand-Target Pair