BDBM50400371 CHEMBL2181684

SMILES: CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2N(CCc12)c1ccc(F)cn1

InChI Key: InChIKey=SSNDJZBLMUHRNM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50400371 (CHEMBL2181684) Show SMILES CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2N(CCc12)c1ccc(F)cn1 Show InChI InChI=1S/C20H24FN5O3/c1-13(2)28-20(27)25-8-5-15(6-9-25)29-19-16-7-10-26(18(16)23-12-24-19)17-4-3-14(21)11-22-17/h3-4,11-13,15H,5-10H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-expressing 6CRE-luciferase gene after 5 hrs by luciferase reporter gene assay				J Med Chem 55: 10972-94 (2012) Article DOI: 10.1021/jm301404a BindingDB Entry DOI: 10.7270/Q2RJ4KMK
					More data for this Ligand-Target Pair