BindingDB logo
myBDB logout

BDBM50400372 CHEMBL2181683

SMILES: CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2N(CCc12)c1ccc(cn1)C#N

InChI Key: InChIKey=LGVAIDIPCQUDQU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400372   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))		BDBM50400372
PNG
(CHEMBL2181683)
Show SMILES CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2N(CCc12)c1ccc(cn1)C#N
Show InChI InChI=1S/C21H24N6O3/c1-14(2)29-21(28)26-8-5-16(6-9-26)30-20-17-7-10-27(19(17)24-13-25-20)18-4-3-15(11-22)12-23-18/h3-4,12-14,16H,5-10H2,1-2H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 794n/an/an/an/a



GlaxoSmithKline Research& Development

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-expressing 6CRE-luciferase gene after 5 hrs by luciferase reporter gene assay

J Med Chem 55: 10972-94 (2012)


Article DOI: 10.1021/jm301404a
BindingDB Entry DOI: 10.7270/Q2RJ4KMK
More data for this
Ligand-Target Pair