BDBM50400404 CHEMBL2177786

SMILES: COC(=O)N1CCC(CC1)Oc1ncnc2N(CCc12)c1ccc(cc1F)S(C)(=O)=O

InChI Key: InChIKey=IYPJRHVRZMQIPD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50400404 (CHEMBL2177786) Show SMILES COC(=O)N1CCC(CC1)Oc1ncnc2N(CCc12)c1ccc(cc1F)S(C)(=O)=O Show InChI InChI=1S/C20H23FN4O5S/c1-29-20(26)24-8-5-13(6-9-24)30-19-15-7-10-25(18(15)22-12-23-19)17-4-3-14(11-16(17)21)31(2,27)28/h3-4,11-13H,5-10H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
GlaxoSmithKline Research& Development Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-expressing 6CRE-luciferase gene after 5 hrs by luciferase reporter gene assay				J Med Chem 55: 10972-94 (2012) Article DOI: 10.1021/jm301404a BindingDB Entry DOI: 10.7270/Q2RJ4KMK
					More data for this Ligand-Target Pair