BDBM50401111 CHEMBL2204479

SMILES: Cc1c(Cc2ccc(=O)n(Cc3ccc(cc3)C(O)(C(F)(F)F)C(F)(F)F)n2)c2cc(F)ccc2n1CC(O)=O

InChI Key: InChIKey=WUMIHSIFGFZCQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50401111 (CHEMBL2204479) Show SMILES Cc1c(Cc2ccc(=O)n(Cc3ccc(cc3)C(O)(C(F)(F)F)C(F)(F)F)n2)c2cc(F)ccc2n1CC(O)=O Show InChI InChI=1S/C26H20F7N3O4/c1-14-19(20-10-17(27)6-8-21(20)35(14)13-23(38)39)11-18-7-9-22(37)36(34-18)12-15-2-4-16(5-3-15)24(40,25(28,29)30)26(31,32)33/h2-10,40H,11-13H2,1H3,(H,38,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in CHO-K1 cells after 30 min by FRET method				J Med Chem 55: 5088-109 (2012) Article DOI: 10.1021/jm300007n BindingDB Entry DOI: 10.7270/Q2S75HH0
					More data for this Ligand-Target Pair