BDBM50401264 CHEMBL2206918

SMILES: Cc1nc(N)nc(n1)-c1cc(Cl)cnc1Nc1cnc(Cl)c(NS(C)(=O)=O)c1

InChI Key: InChIKey=QNTWFBRDSGVBHE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50401264 (CHEMBL2206918) Show SMILES Cc1nc(N)nc(n1)-c1cc(Cl)cnc1Nc1cnc(Cl)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C15H14Cl2N8O2S/c1-7-21-14(24-15(18)22-7)10-3-8(16)5-20-13(10)23-9-4-11(12(17)19-6-9)25-28(2,26)27/h3-6,25H,1-2H3,(H,20,23)(H2,18,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal polyHis-tagged PI3K p110alpha expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...				Bioorg Med Chem Lett 22: 5714-20 (2012) Article DOI: 10.1016/j.bmcl.2012.06.078 BindingDB Entry DOI: 10.7270/Q2MG7QNW
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