BDBM50401295 CHEMBL2204539
SMILES: CC(C)Oc1nc(nc2CCN(Cc12)C(=O)N(C)c1cn[nH]c1)-c1ccc(Cl)nc1
InChI Key: InChIKey=HUDAVWQNVFDFNL-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human)) | BDBM50401295 (CHEMBL2204539) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of PDE10A | Bioorg Med Chem Lett 22: 5903-8 (2012) Article DOI: 10.1016/j.bmcl.2012.07.072 BindingDB Entry DOI: 10.7270/Q23J3F3X | |||||||||||
More data for this Ligand-Target Pair |