BDBM50401553 CHEMBL2207085

SMILES: Cn1nnnc1Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=DLTXTHJGLDWETN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50401553 (CHEMBL2207085) Show SMILES Cn1nnnc1Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H12Cl3N5O2S/c1-23-15(19-21-22-23)6-9-2-3-10(16)7-14(9)20-26(24,25)11-4-5-12(17)13(18)8-11/h2-5,7-8,20H,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity to CCR2 by 35S-gamma-GTP membrane assay				Bioorg Med Chem Lett 22: 7252-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.020 BindingDB Entry DOI: 10.7270/Q21J9BZJ
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50401553 (CHEMBL2207085) Show SMILES Cn1nnnc1Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H12Cl3N5O2S/c1-23-15(19-21-22-23)6-9-2-3-10(16)7-14(9)20-26(24,25)11-4-5-12(17)13(18)8-11/h2-5,7-8,20H,6H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity to CCR4 by 35S-gamma-GTP membrane assay				Bioorg Med Chem Lett 22: 7252-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.020 BindingDB Entry DOI: 10.7270/Q21J9BZJ
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50401553 (CHEMBL2207085) Show SMILES Cn1nnnc1Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H12Cl3N5O2S/c1-23-15(19-21-22-23)6-9-2-3-10(16)7-14(9)20-26(24,25)11-4-5-12(17)13(18)8-11/h2-5,7-8,20H,6H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity to CCR1 by 35S-gamma-GTP membrane assay				Bioorg Med Chem Lett 22: 7252-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.020 BindingDB Entry DOI: 10.7270/Q21J9BZJ
					More data for this Ligand-Target Pair