BDBM50401568 CHEMBL2207079

SMILES: Cc1cc(C)n(Cc2ccc(cc2NS(=O)(=O)c2ccc(Cl)cc2)C(F)(F)F)n1

InChI Key: InChIKey=HMHYOXVYXVHCTN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50401568 (CHEMBL2207079) Show SMILES Cc1cc(C)n(Cc2ccc(cc2NS(=O)(=O)c2ccc(Cl)cc2)C(F)(F)F)n1 Show InChI InChI=1S/C19H17ClF3N3O2S/c1-12-9-13(2)26(24-12)11-14-3-4-15(19(21,22)23)10-18(14)25-29(27,28)17-7-5-16(20)6-8-17/h3-10,25H,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity to CCR2 by 35S-gamma-GTP membrane assay				Bioorg Med Chem Lett 22: 7252-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.020 BindingDB Entry DOI: 10.7270/Q21J9BZJ
					More data for this Ligand-Target Pair