BDBM50401746 CHEMBL2207133
SMILES: C[C@H](NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCC(O)=O
InChI Key: InChIKey=VQDVDJQYFIVYCL-JQWIXIFHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidyl-glycine alpha-amidating monooxygenase (Homo sapiens (Human)) | BDBM50401746 (CHEMBL2207133) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysis | Bioorg Med Chem Lett 22: 7015-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.004 BindingDB Entry DOI: 10.7270/Q2VT1T73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-glycine alpha-amidating monooxygenase (Homo sapiens (Human)) | BDBM50401746 (CHEMBL2207133) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysis | Bioorg Med Chem Lett 22: 7015-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.004 BindingDB Entry DOI: 10.7270/Q2VT1T73 | |||||||||||
More data for this Ligand-Target Pair |