BDBM50402071 CHEMBL2206015

SMILES: COc1cc(\C=C2/C(=O)Nc3ccc(Cl)cc23)ccc1OCCN(C)C

InChI Key: InChIKey=JUWUNGUBIMHNLC-YBEGLDIGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50402071 (CHEMBL2206015) Show SMILES COc1cc(\C=C2/C(=O)Nc3ccc(Cl)cc23)ccc1OCCN(C)C Show InChI InChI=1S/C20H21ClN2O3/c1-23(2)8-9-26-18-7-4-13(11-19(18)25-3)10-16-15-12-14(21)5-6-17(15)22-20(16)24/h4-7,10-12H,8-9H2,1-3H3,(H,22,24)/b16-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE method				Bioorg Med Chem Lett 22: 7634-40 (2012) Article DOI: 10.1016/j.bmcl.2012.10.016 BindingDB Entry DOI: 10.7270/Q2SX6FCN
					More data for this Ligand-Target Pair