BDBM50402212 CHEMBL2203970

SMILES: On1c(cc(cc1=O)-c1ccc(cc1)C(F)(F)F)-c1ccccc1

InChI Key: InChIKey=OAPXMARAIVEYNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyoxalase 1 (GLO1) (Homo sapiens (Human))	BDBM50402212 (CHEMBL2203970) Show SMILES On1c(cc(cc1=O)-c1ccc(cc1)C(F)(F)F)-c1ccccc1 Show InChI InChI=1S/C18H12F3NO2/c19-18(20,21)15-8-6-12(7-9-15)14-10-16(22(24)17(23)11-14)13-4-2-1-3-5-13/h1-11,24H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...				Bioorg Med Chem Lett 22: 7486-9 (2012) Article DOI: 10.1016/j.bmcl.2012.10.045 BindingDB Entry DOI: 10.7270/Q2RX9D8Q
					More data for this Ligand-Target Pair