BDBM50402344 CHEMBL2203321

SMILES: FC(F)(F)c1ccc(NC(=O)Nc2cccc(Oc3ccc4nccn4n3)c2)cc1

InChI Key: InChIKey=JSYFYBXDIWICOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50402344 (CHEMBL2203321) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2cccc(Oc3ccc4nccn4n3)c2)cc1 Show InChI InChI=1S/C20H14F3N5O2/c21-20(22,23)13-4-6-14(7-5-13)25-19(29)26-15-2-1-3-16(12-15)30-18-9-8-17-24-10-11-28(17)27-18/h1-12H,(H2,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysis				Bioorg Med Chem 20: 7051-8 (2012) Article DOI: 10.1016/j.bmc.2012.10.004 BindingDB Entry DOI: 10.7270/Q2GF0VN9
					More data for this Ligand-Target Pair