null

SMILES: COc1cccc(SC[C@@H](O)CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)c1

InChI Key: InChIKey=VDFDTTRCUDMUDX-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50402808 (CHEMBL2208421) Show SMILES COc1cccc(SC[C@@H](O)CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)c1 |r| Show InChI InChI=1S/C21H25Cl2NO3S/c1-26-17-3-2-4-19(11-17)28-14-15(25)13-24-9-7-16(8-10-24)27-18-5-6-20(22)21(23)12-18/h2-6,11-12,15-16,25H,7-10,13-14H2,1H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hr				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50402808 (CHEMBL2208421) Show SMILES COc1cccc(SC[C@@H](O)CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)c1 |r| Show InChI InChI=1S/C21H25Cl2NO3S/c1-26-17-3-2-4-19(11-17)28-14-15(25)13-24-9-7-16(8-10-24)27-18-5-6-20(22)21(23)12-18/h2-6,11-12,15-16,25H,7-10,13-14H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair