Found 6 hits for monomerid = 50402860 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50402860
(CHEMBL2205588)Show SMILES COC1CN(C1)C(=O)c1c(NC(=O)c2ccccc2C(F)(F)F)sc2COCCc12 Show InChI InChI=1S/C20H19F3N2O4S/c1-28-11-8-25(9-11)19(27)16-13-6-7-29-10-15(13)30-18(16)24-17(26)12-4-2-3-5-14(12)20(21,22)23/h2-5,11H,6-10H2,1H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 899 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Rattus norvegicus (Rat)) | BDBM50402860
(CHEMBL2205588)Show SMILES COC1CN(C1)C(=O)c1c(NC(=O)c2ccccc2C(F)(F)F)sc2COCCc12 Show InChI InChI=1S/C20H19F3N2O4S/c1-28-11-8-25(9-11)19(27)16-13-6-7-29-10-15(13)30-18(16)24-17(26)12-4-2-3-5-14(12)20(21,22)23/h2-5,11H,6-10H2,1H3,(H,24,26) | KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50402860
(CHEMBL2205588)Show SMILES COC1CN(C1)C(=O)c1c(NC(=O)c2ccccc2C(F)(F)F)sc2COCCc12 Show InChI InChI=1S/C20H19F3N2O4S/c1-28-11-8-25(9-11)19(27)16-13-6-7-29-10-15(13)30-18(16)24-17(26)12-4-2-3-5-14(12)20(21,22)23/h2-5,11H,6-10H2,1H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50402860
(CHEMBL2205588)Show SMILES COC1CN(C1)C(=O)c1c(NC(=O)c2ccccc2C(F)(F)F)sc2COCCc12 Show InChI InChI=1S/C20H19F3N2O4S/c1-28-11-8-25(9-11)19(27)16-13-6-7-29-10-15(13)30-18(16)24-17(26)12-4-2-3-5-14(12)20(21,22)23/h2-5,11H,6-10H2,1H3,(H,24,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50402860
(CHEMBL2205588)Show SMILES COC1CN(C1)C(=O)c1c(NC(=O)c2ccccc2C(F)(F)F)sc2COCCc12 Show InChI InChI=1S/C20H19F3N2O4S/c1-28-11-8-25(9-11)19(27)16-13-6-7-29-10-15(13)30-18(16)24-17(26)12-4-2-3-5-14(12)20(21,22)23/h2-5,11H,6-10H2,1H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Agonist activity at human CB2 receptor after 4 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50402860
(CHEMBL2205588)Show SMILES COC1CN(C1)C(=O)c1c(NC(=O)c2ccccc2C(F)(F)F)sc2COCCc12 Show InChI InChI=1S/C20H19F3N2O4S/c1-28-11-8-25(9-11)19(27)16-13-6-7-29-10-15(13)30-18(16)24-17(26)12-4-2-3-5-14(12)20(21,22)23/h2-5,11H,6-10H2,1H3,(H,24,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.96E+3 | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Agonist activity at human CB1 receptor after 4 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |