BDBM50402964 CHEMBL2206776

SMILES: Clc1ccccc1-n1ncc2c(SCC(=O)Nc3ccccc3)ncnc12

InChI Key: InChIKey=DHXWXYRCRSGNTI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50402964 (CHEMBL2206776) Show SMILES Clc1ccccc1-n1ncc2c(SCC(=O)Nc3ccccc3)ncnc12 Show InChI InChI=1S/C19H14ClN5OS/c20-15-8-4-5-9-16(15)25-18-14(10-23-25)19(22-12-21-18)27-11-17(26)24-13-6-2-1-3-7-13/h1-10,12H,11H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Activation of human glucokinase				Bioorg Med Chem Lett 22: 7302-5 (2012) Article DOI: 10.1016/j.bmcl.2012.10.090 BindingDB Entry DOI: 10.7270/Q2BK1DJ3
					More data for this Ligand-Target Pair