BDBM50402998 CHEMBL2207433

SMILES: COc1ccc(cn1)-c1cc(NC(=O)Nc2cc(nn2-c2ccc(C)cc2)C(C)(C)C)[nH]n1

InChI Key: InChIKey=FABCYRRRMWWGRH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human))	BDBM50402998 (CHEMBL2207433) Show SMILES COc1ccc(cn1)-c1cc(NC(=O)Nc2cc(nn2-c2ccc(C)cc2)C(C)(C)C)[nH]n1 Show InChI InChI=1S/C24H27N7O2/c1-15-6-9-17(10-7-15)31-21(13-19(30-31)24(2,3)4)27-23(32)26-20-12-18(28-29-20)16-8-11-22(33-5)25-14-16/h6-14H,1-5H3,(H3,26,27,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	361	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate addition				Bioorg Med Chem Lett 22: 7523-9 (2012) Article DOI: 10.1016/j.bmcl.2012.10.039 BindingDB Entry DOI: 10.7270/Q2319X2C
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50402998 (CHEMBL2207433) Show SMILES COc1ccc(cn1)-c1cc(NC(=O)Nc2cc(nn2-c2ccc(C)cc2)C(C)(C)C)[nH]n1 Show InChI InChI=1S/C24H27N7O2/c1-15-6-9-17(10-7-15)31-21(13-19(30-31)24(2,3)4)27-23(32)26-20-12-18(28-29-20)16-8-11-22(33-5)25-14-16/h6-14H,1-5H3,(H3,26,27,28,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	524	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assay				Bioorg Med Chem Lett 22: 7523-9 (2012) Article DOI: 10.1016/j.bmcl.2012.10.039 BindingDB Entry DOI: 10.7270/Q2319X2C
					More data for this Ligand-Target Pair