BDBM50403082 CHEMBL2216756

SMILES: Nc1ncc(nc1C(=O)c1cccnc1)-c1ccc(Cl)c(c1)S(=O)(=O)Nc1ccccc1

InChI Key: InChIKey=OIUSEOHHFQQDOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403082 (CHEMBL2216756) Show SMILES Nc1ncc(nc1C(=O)c1cccnc1)-c1ccc(Cl)c(c1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C22H16ClN5O3S/c23-17-9-8-14(11-19(17)32(30,31)28-16-6-2-1-3-7-16)18-13-26-22(24)20(27-18)21(29)15-5-4-10-25-12-15/h1-13,28H,(H2,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair