BDBM50403093 CHEMBL2216858

SMILES: C1CN(CCO1)c1nc(cc2ccccc12)-c1cccc2[nH]ccc12

InChI Key: InChIKey=NTTUVIVSZDBDRW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403093 (CHEMBL2216858) Show SMILES C1CN(CCO1)c1nc(cc2ccccc12)-c1cccc2[nH]ccc12 Show InChI InChI=1S/C21H19N3O/c1-2-5-16-15(4-1)14-20(23-21(16)24-10-12-25-13-11-24)17-6-3-7-19-18(17)8-9-22-19/h1-9,14,22H,10-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair