BDBM50403401 CHEMBL276548

SMILES: CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1cccc(NS(C)(=O)=O)c1)-c1ccncc1

InChI Key: InChIKey=GTHHJTYXQHZWRY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50403401 (CHEMBL276548) Show SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1cccc(NS(C)(=O)=O)c1)-c1ccncc1 Show InChI InChI=1S/C22H20N4O3S2/c1-30(27)19-8-6-16(7-9-19)22-24-20(15-10-12-23-13-11-15)21(25-22)17-4-3-5-18(14-17)26-31(2,28)29/h3-14,26H,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytes				Bioorg Med Chem Lett 5: 1171-1176 (1995) Article DOI: 10.1016/0960-894X(95)00189-Z BindingDB Entry DOI: 10.7270/Q28S4PV1
					More data for this Ligand-Target Pair