BDBM50403574 CHEMBL4169713

SMILES: Oc1cccc(CC2Cc3cccc(OCC4CCCCC4)c3C2=O)c1

InChI Key: InChIKey=MPPXCGRXUNGPFS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-5 (Mus musculus)	BDBM50403574 (CHEMBL4169713) Show SMILES Oc1cccc(CC2Cc3cccc(OCC4CCCCC4)c3C2=O)c1 Show InChI InChI=1S/C16H16ClNO4S/c17-13-6-10-15(11-7-13)23(21,22)18-14-8-4-12(5-9-14)2-1-3-16(19)20/h4-11,18H,1-3H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay				Eur J Med Chem 152: 65-75 (2018) Article DOI: 10.1016/j.ejmech.2018.04.030 BindingDB Entry DOI: 10.7270/Q279477F
					More data for this Ligand-Target Pair