BDBM50403601 CHEMBL1163396

SMILES: Oc1ccc(Cc2coc3cccc(OCC4CCCCC4)c3c2=O)cc1

InChI Key: InChIKey=GOAHXSVKIFPWHR-XZZFYQAUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-5 (Mus musculus)	BDBM50403601 (CHEMBL1163396) Show SMILES Oc1ccc(Cc2coc3cccc(OCC4CCCCC4)c3c2=O)cc1 Show InChI InChI=1S/C23H33NO4/c1-2-3-4-7-14-22(26)24-16-18(11-6-5-8-15-23(27)28)20(17-24)19-12-9-10-13-21(19)25/h5-6,9-10,12-13,18,20,25H,2-4,7-8,11,14-17H2,1H3,(H,27,28)/b6-5-/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assay				Eur J Med Chem 152: 65-75 (2018) Article DOI: 10.1016/j.ejmech.2018.04.030 BindingDB Entry DOI: 10.7270/Q279477F
					More data for this Ligand-Target Pair