null
SMILES: CN(C)CCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F
InChI Key: InChIKey=GOHPIKDATUAMSC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50403675 (CHEMBL314438) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Contractile effects antagonized by mepyramine (0.3-100 nM) against Histamine H1 receptor in guinea pig ileum | Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50403675 (CHEMBL314438) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileum | Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50403675 (CHEMBL314438) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.41 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Compound was tested for the contractile effects antagonized by mepyramine (1-1000 nM) against Histamine H1 receptor of guinea pig aorta. | Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor (Cavia porcellus) | BDBM50403675 (CHEMBL314438) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Compound was tested for its agonist activity against M3-acetylcholine receptor of guinea pig ileum. | Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V | |||||||||||
More data for this Ligand-Target Pair |