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SMILES: Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)OCc2ccccc2)c1=O

InChI Key: InChIKey=UDHGWZLFFYNWRQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403892   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50403892
PNG
(CHEMBL3142818 | CHEMBL321135)
Show SMILES Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)OCc2ccccc2)c1=O |r|
Show InChI InChI=1S/C25H36N2O8Si/c1-16-12-27(23-21(20(30)18(14-28)34-23)35-36(5,6)25(2,3)4)24(32)26(22(16)31)13-19(29)33-15-17-10-8-7-9-11-17/h7-12,18,20-21,23,28,30H,13-15H2,1-6H3
PDB
MMDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 4.00E+3n/an/an/an/a



Instituto de Química Médica (C.S.I.C.)

Curated by ChEMBL


Assay Description
Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cells

Bioorg Med Chem Lett 11: 3085-8 (2001)


BindingDB Entry DOI: 10.7270/Q2QC02S2
More data for this
Ligand-Target Pair