BDBM50403957 CHEMBL313189

SMILES: CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21

InChI Key: InChIKey=SWGWJQBPCJEQJC-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50403957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Alpha-2A adrenergic receptor				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells using [125I]R91150 as radioligand				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for rat Dopamine receptor D2				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Alpha-2C adrenergic receptor				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligand				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Alpha-1A adrenergic receptor				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Dopamine receptor D3				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells using [3H]mesulergine as radioligand				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Dopamine receptor D2L				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50403957 (CHEMBL313189) Show SMILES CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair