BDBM50403963 CHEMBL83220

SMILES: CN(CC1CC2N(O1)c1ccccc1Cc1ccccc21)C(=O)C(F)(F)F

InChI Key: InChIKey=DQAMCNMFLLPWQR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50403963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50403963 (CHEMBL83220) Show SMILES CN(CC1CC2N(O1)c1ccccc1Cc1ccccc21)C(=O)C(F)(F)F Show InChI InChI=1S/C20H19F3N2O2/c1-24(19(26)20(21,22)23)12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)25(18)27-15/h2-9,15,18H,10-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells using [125I]R91150 as radioligand				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50403963 (CHEMBL83220) Show SMILES CN(CC1CC2N(O1)c1ccccc1Cc1ccccc21)C(=O)C(F)(F)F Show InChI InChI=1S/C20H19F3N2O2/c1-24(19(26)20(21,22)23)12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)25(18)27-15/h2-9,15,18H,10-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligand				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50403963 (CHEMBL83220) Show SMILES CN(CC1CC2N(O1)c1ccccc1Cc1ccccc21)C(=O)C(F)(F)F Show InChI InChI=1S/C20H19F3N2O2/c1-24(19(26)20(21,22)23)12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)25(18)27-15/h2-9,15,18H,10-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	692	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells using [3H]mesulergine as radioligand				Bioorg Med Chem Lett 12: 243-8 (2001) BindingDB Entry DOI: 10.7270/Q23J3F4C
					More data for this Ligand-Target Pair