Found 12 hits for monomerid = 50403974 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H1 receptor expressed in CHO cells by [3H]pyrilamine displacement. |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells by [3H]mesulergine displacement. |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Alpha-2A adrenergic receptor |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells by [125I]R91150 displacement. |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Dopamine receptor D2L |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Dopamine receptor D4 |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 1A receptor |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for rat Dopamine receptor D2 |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Dopamine receptor D3 |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Alpha-1A adrenergic receptor |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Alpha-2C adrenergic receptor |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50403974
(CHEMBL84931)Show InChI InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 302 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen-Cilag
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 12: 249-53 (2001)
BindingDB Entry DOI: 10.7270/Q2ZW1N3V |
More data for this Ligand-Target Pair | |