BDBM50403981 CHEMBL84810

SMILES: CN(C)CC1CC2N(O1)c1ccccc1Cc1cccc(c21)C(F)(F)F

InChI Key: InChIKey=ZNWOCPPAOLYORT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50403981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50403981 (CHEMBL84810) Show SMILES CN(C)CC1CC2N(O1)c1ccccc1Cc1cccc(c21)C(F)(F)F Show InChI InChI=1S/C20H21F3N2O/c1-24(2)12-15-11-18-19-14(7-5-8-16(19)20(21,22)23)10-13-6-3-4-9-17(13)25(18)26-15/h3-9,15,18H,10-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells by [125I]R91150 displacement.				Bioorg Med Chem Lett 12: 249-53 (2001) BindingDB Entry DOI: 10.7270/Q2ZW1N3V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50403981 (CHEMBL84810) Show SMILES CN(C)CC1CC2N(O1)c1ccccc1Cc1cccc(c21)C(F)(F)F Show InChI InChI=1S/C20H21F3N2O/c1-24(2)12-15-11-18-19-14(7-5-8-16(19)20(21,22)23)10-13-6-3-4-9-17(13)25(18)26-15/h3-9,15,18H,10-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells by [3H]mesulergine displacement.				Bioorg Med Chem Lett 12: 249-53 (2001) BindingDB Entry DOI: 10.7270/Q2ZW1N3V
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50403981 (CHEMBL84810) Show SMILES CN(C)CC1CC2N(O1)c1ccccc1Cc1cccc(c21)C(F)(F)F Show InChI InChI=1S/C20H21F3N2O/c1-24(2)12-15-11-18-19-14(7-5-8-16(19)20(21,22)23)10-13-6-3-4-9-17(13)25(18)26-15/h3-9,15,18H,10-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Binding affinity at human cloned Histamine H1 receptor expressed in CHO cells by [3H]pyrilamine displacement.				Bioorg Med Chem Lett 12: 249-53 (2001) BindingDB Entry DOI: 10.7270/Q2ZW1N3V
					More data for this Ligand-Target Pair