BDBM50404135 CHEMBL146511

SMILES: Cc1ccc(NC(=O)c2sccc2Cl)c(c1)C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=SFGLUYLLXHBRQN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50404135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50404135 (CHEMBL146511) Show SMILES Cc1ccc(NC(=O)c2sccc2Cl)c(c1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C19H14ClFN2O2S/c1-11-2-7-16(23-19(25)17-15(20)8-9-26-17)14(10-11)18(24)22-13-5-3-12(21)4-6-13/h2-10H,1H3,(H,22,24)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition constant against human factor Xa				Bioorg Med Chem Lett 13: 507-11 (2003) BindingDB Entry DOI: 10.7270/Q21N829C
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50404135 (CHEMBL146511) Show SMILES Cc1ccc(NC(=O)c2sccc2Cl)c(c1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C19H14ClFN2O2S/c1-11-2-7-16(23-19(25)17-15(20)8-9-26-17)14(10-11)18(24)22-13-5-3-12(21)4-6-13/h2-10H,1H3,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition constant against human thrombin				Bioorg Med Chem Lett 13: 507-11 (2003) BindingDB Entry DOI: 10.7270/Q21N829C
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50404135 (CHEMBL146511) Show SMILES Cc1ccc(NC(=O)c2sccc2Cl)c(c1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C19H14ClFN2O2S/c1-11-2-7-16(23-19(25)17-15(20)8-9-26-17)14(10-11)18(24)22-13-5-3-12(21)4-6-13/h2-10H,1H3,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition constant against bovine trypsin				Bioorg Med Chem Lett 13: 507-11 (2003) BindingDB Entry DOI: 10.7270/Q21N829C
					More data for this Ligand-Target Pair