BDBM50404233 CHEMBL283759

SMILES: Clc1cccc(c1)-c1ccc2NC(=S)C3(CCCC3)c2c1

InChI Key: InChIKey=MKIGJOKMZUSJGM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50404233 (CHEMBL283759) Show SMILES Clc1cccc(c1)-c1ccc2NC(=S)C3(CCCC3)c2c1 Show InChI InChI=1S/C18H16ClNS/c19-14-5-3-4-12(10-14)13-6-7-16-15(11-13)18(17(21)20-16)8-1-2-9-18/h3-7,10-11H,1-2,8-9H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Effective concentration of progesterone receptor agonist induction of alkaline phosphatase activity in human T47D breast carcinoma cells				Bioorg Med Chem Lett 13: 1317-20 (2003) BindingDB Entry DOI: 10.7270/Q2WS8SNP
					More data for this Ligand-Target Pair