BDBM50404350 CHEMBL46329

SMILES: COC(=O)\C=C\CC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key: InChIKey=NMFHEHBJCPXSJD-YRNVUSSQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50404350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50404350 (CHEMBL46329) Show SMILES COC(=O)\C=C\CC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:26| Show InChI InChI=1S/C25H27NO4/c1-15-14-25(2,3)26-17-13-12-16-23-18(28-4)8-6-9-19(23)30-20(24(16)22(15)17)10-7-11-21(27)29-5/h6-9,11-14,20,26H,10H2,1-5H3/b11-7+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transcriptional repression in CV-1 cells expressing glucocorticoid receptor				Bioorg Med Chem Lett 14: 1721-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.044 BindingDB Entry DOI: 10.7270/Q2KP81M9
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50404350 (CHEMBL46329) Show SMILES COC(=O)\C=C\CC1Oc2cccc(OC)c2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:26| Show InChI InChI=1S/C25H27NO4/c1-15-14-25(2,3)26-17-13-12-16-23-18(28-4)8-6-9-19(23)30-20(24(16)22(15)17)10-7-11-21(27)29-5/h6-9,11-14,20,26H,10H2,1-5H3/b11-7+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of transcriptional activation in CV-1 cells expressing glucocorticoid receptor				Bioorg Med Chem Lett 14: 1721-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.044 BindingDB Entry DOI: 10.7270/Q2KP81M9
					More data for this Ligand-Target Pair