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SMILES: [#6]-[#7]-[#6](-[#7]-c1cccc(c1)-c1csc(\[#7]=[#6](\[#7])-[#7])n1)=[#7]C#N

InChI Key: InChIKey=QAJXFAVPCJPZCT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404955   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50404955
PNG
(CHEMBL441965)
Show SMILES [#6]-[#7]-[#6](-[#7]-c1cccc(c1)-c1csc(\[#7]=[#6](\[#7])-[#7])n1)=[#7]C#N |w:19.21|
Show InChI InChI=1S/C13H14N8S/c1-17-12(18-7-14)19-9-4-2-3-8(5-9)10-6-22-13(20-10)21-11(15)16/h2-6H,1H3,(H2,17,18,19)(H4,15,16,20,21)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
 316n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated in vitro for Histamine H2 receptor inhibition using the dimaprit stimulated chronotropic response of the guinea pig atrium

J Med Chem 26: 140-4 (1983)


BindingDB Entry DOI: 10.7270/Q2R212KZ
More data for this
Ligand-Target Pair