BindingDB logo
myBDB logout

null

SMILES: [#6]-[#7]-c1ns(=O)nc1-[#7]-c1cccc(c1)-c1csc(\[#7]=[#6](/[#7])-[#7])n1

InChI Key: InChIKey=ZOYUVGPUVJZSKC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404956   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50404956
PNG
(CHEMBL284556)
Show SMILES [#6]-[#7]-c1ns(=O)nc1-[#7]-c1cccc(c1)-c1csc(\[#7]=[#6](/[#7])-[#7])n1
Show InChI InChI=1S/C13H14N8OS2/c1-16-10-11(21-24(22)20-10)17-8-4-2-3-7(5-8)9-6-23-13(18-9)19-12(14)15/h2-6H,1H3,(H,16,20)(H,17,21)(H4,14,15,18,19)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 398n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated in vitro for Histamine H2 receptor inhibition using the dimaprit stimulated chronotropic response of the guinea pig atrium

J Med Chem 26: 140-4 (1983)


BindingDB Entry DOI: 10.7270/Q2R212KZ
More data for this
Ligand-Target Pair