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SMILES: CNC([CH-][N+]([O-])=O)=[NH+]c1cccc(c1)-c1nc[nH]c1C

InChI Key: InChIKey=VPGSYLFDIXEBIY-UHFFFAOYSA-O

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404957   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50404957
PNG
(CHEMBL33996)
Show SMILES CNC([CH-][N+]([O-])=O)=[NH+]c1cccc(c1)-c1nc[nH]c1C |w:7.7|
Show InChI InChI=1S/C13H14N5O2/c1-9-13(16-8-15-9)10-4-3-5-11(6-10)17-12(14-2)7-18(19)20/h3-8H,1-2H3,(H,14,17)(H,15,16)/q-1/p+1
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
 1.58E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated in vitro for Histamine H2 receptor inhibition using the dimaprit stimulated chronotropic response of the guinea pig atrium

J Med Chem 26: 140-4 (1983)


BindingDB Entry DOI: 10.7270/Q2R212KZ
More data for this
Ligand-Target Pair