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BDBM50404958 CHEMBL284743

SMILES: [#7]\[#6](-[#7])=[#7]/c1nc(cs1)-c1cccc(-[#7]-c2ns(=O)nc2-[#7])c1

InChI Key: InChIKey=QZGGKSUVWHNKCW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404958   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50404958
PNG
(CHEMBL284743)
Show SMILES [#7]\[#6](-[#7])=[#7]/c1nc(cs1)-c1cccc(-[#7]-c2ns(=O)nc2-[#7])c1
Show InChI InChI=1S/C12H12N8OS2/c13-9-10(20-23(21)19-9)16-7-3-1-2-6(4-7)8-5-22-12(17-8)18-11(14)15/h1-5H,(H2,13,19)(H,16,20)(H4,14,15,17,18)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 316n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Evaluated in vitro for Histamine H2 receptor inhibition using the dimaprit stimulated chronotropic response of the guinea pig atrium

J Med Chem 26: 140-4 (1983)


BindingDB Entry DOI: 10.7270/Q2R212KZ
More data for this
Ligand-Target Pair