BDBM50405032 CHEMBL4159472

SMILES: [H][C@@]12CC(=O)C=C[C@]11N([C@@H](C(=O)N2)c2ccc(cc2)[N+]([O-])=O)C(=O)C=C1c1ccccc1

InChI Key: InChIKey=MEYYCPOTPKLGNY-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50405032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50405032 (CHEMBL4159472) Show SMILES [H][C@@]12CC(=O)C=C[C@]11N([C@@H](C(=O)N2)c2ccc(cc2)[N+]([O-])=O)C(=O)C=C1c1ccccc1 |r,c:5,27| Show InChI InChI=1S/C17H21N3O6/c1-18-6-8-19(9-7-18)5-2-10-25-12-3-4-13-14(11-12)26-17(22)15(16(13)21)20(23)24/h3-4,11,21H,2,5-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.263	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...				Eur J Med Chem 152: 148-159 (2018) Article DOI: 10.1016/j.ejmech.2018.04.020 BindingDB Entry DOI: 10.7270/Q2QC063R
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50405032 (CHEMBL4159472) Show SMILES [H][C@@]12CC(=O)C=C[C@]11N([C@@H](C(=O)N2)c2ccc(cc2)[N+]([O-])=O)C(=O)C=C1c1ccccc1 |r,c:5,27| Show InChI InChI=1S/C17H21N3O6/c1-18-6-8-19(9-7-18)5-2-10-25-12-3-4-13-14(11-12)26-17(22)15(16(13)21)20(23)24/h3-4,11,21H,2,5-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...				Eur J Med Chem 152: 148-159 (2018) Article DOI: 10.1016/j.ejmech.2018.04.020 BindingDB Entry DOI: 10.7270/Q2QC063R
					More data for this Ligand-Target Pair