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SMILES: Cc1nc[nH]c1CSCCNC(=N)NCCSCc1nccs1

InChI Key: InChIKey=LEAYJBKAPNKTOJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50405164   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50405164
PNG
(CHEMBL1744351)
Show SMILES Cc1nc[nH]c1CSCCNC(=N)NCCSCc1nccs1
Show InChI InChI=1S/C14H22N6S3/c1-11-12(20-10-19-11)8-21-5-2-17-14(15)18-3-6-22-9-13-16-4-7-23-13/h4,7,10H,2-3,5-6,8-9H2,1H3,(H,19,20)(H3,15,17,18)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/a 776n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonistic activity against H2 receptor in guinea pig.

J Med Chem 28: 1414-22 (1985)


BindingDB Entry DOI: 10.7270/Q2P27096
More data for this
Ligand-Target Pair