BDBM50405914 CHEMBL4162777

SMILES: Fc1cccc(CCNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)-c2ccc(COc3cccc(c3)C(F)(F)F)cc2)c1

InChI Key: InChIKey=UVVSNULRSVITMO-RQOWECAXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50405914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50405914 (CHEMBL4162777) Show SMILES Fc1cccc(CCNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)-c2ccc(COc3cccc(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C15H24O3S/c1-19-10-12-11(13-8-9-14(12)18-13)6-4-2-3-5-7-15(16)17/h2,4,11-14H,3,5-10H2,1H3,(H,16,17)/b4-2-	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused erbB2 expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate after 60 mins in...				Eur J Med Chem 152: 253-263 (2018) Article DOI: 10.1016/j.ejmech.2018.04.018 BindingDB Entry DOI: 10.7270/Q2XW4NC8
					More data for this Ligand-Target Pair
Receptor protein-tyrosine kinase erbB-4 (Homo sapiens (Human))	BDBM50405914 (CHEMBL4162777) Show SMILES Fc1cccc(CCNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)-c2ccc(COc3cccc(c3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C15H24O3S/c1-19-10-12-11(13-8-9-14(12)18-13)6-4-2-3-5-7-15(16)17/h2,4,11-14H,3,5-10H2,1H3,(H,16,17)/b4-2-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused erbB4 expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate after 60 mins in...				Eur J Med Chem 152: 253-263 (2018) Article DOI: 10.1016/j.ejmech.2018.04.018 BindingDB Entry DOI: 10.7270/Q2XW4NC8
					More data for this Ligand-Target Pair