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SMILES: COP(=O)(CCc1c(C)cc(C)cc1-c1ccc(F)c(C)c1)C[C@@H](O)CC(O)=O

InChI Key: InChIKey=UQEWOVNIGZJYNL-STFFIMJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406117   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Rattus norvegicus (rat))		BDBM50406117
PNG
(CHEMBL101493)
Show SMILES COP(=O)(CCc1c(C)cc(C)cc1-c1ccc(F)c(C)c1)C[C@@H](O)CC(O)=O
Show InChI InChI=1S/C22H28FO5P/c1-14-9-15(2)19(20(10-14)17-5-6-21(23)16(3)11-17)7-8-29(27,28-4)13-18(24)12-22(25)26/h5-6,9-11,18,24H,7-8,12-13H2,1-4H3,(H,25,26)/t18-,29?/m0/s1
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PC cid
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Similars
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of rat microsomal HMG-CoA reductase activity by 50%

J Med Chem 33: 2952-6 (1990)


BindingDB Entry DOI: 10.7270/Q22Z16Q5
More data for this
Ligand-Target Pair