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SMILES: Ic1ccccc1C(=O)NCCN1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=OHSGGKPQDGFXBB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406166   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50406166
PNG
(CHEMBL100858)
Show SMILES Ic1ccccc1C(=O)NCCN1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H24IN3O/c21-19-9-5-4-8-18(19)20(25)22-10-11-23-12-14-24(15-13-23)16-17-6-2-1-3-7-17/h1-9H,10-16H2,(H,22,25)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 345n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum

J Med Chem 33: 2970-6 (1990)


BindingDB Entry DOI: 10.7270/Q2Z89DMH
More data for this
Ligand-Target Pair