BDBM50406198 CHEMBL145035

SMILES: CC(C)COC(=O)N(C)c1nc2ccccc2c(=O)o1

InChI Key: InChIKey=HTVAQWWUWWYKIY-UHFFFAOYSA-N

Data: 1 KI  1 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50406198 (CHEMBL145035) Show SMILES CC(C)COC(=O)N(C)c1nc2ccccc2c(=O)o1 Show InChI InChI=1S/C14H16N2O4/c1-9(2)8-19-14(18)16(3)13-15-11-7-5-4-6-10(11)12(17)20-13/h4-7,9H,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.51	n/a	n/a	n/a	n/a	0.000813	3.02E+5	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Component deacylation rate constant for interaction with human leukocyte elastase				J Med Chem 33: 464-79 (1990) Checked by Author BindingDB Entry DOI: 10.7270/Q2PR7X6X
					More data for this Ligand-Target Pair