BDBM50406254 CHEMBL344969

SMILES: CC(C)Nc1nc2cc(cc(C)c2c(=O)o1)N(C)C

InChI Key: InChIKey=GFCPSNKLIMJVSG-UHFFFAOYSA-N

Data: 1 KI  1 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50406254 (CHEMBL344969) Show SMILES CC(C)Nc1nc2cc(cc(C)c2c(=O)o1)N(C)C Show InChI InChI=1S/C14H19N3O2/c1-8(2)15-14-16-11-7-10(17(4)5)6-9(3)12(11)13(18)19-14/h6-8H,1-5H3,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.26E+3	n/a	n/a	n/a	n/a	0.000129	102	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Component deacylation rate constant for interaction with human leukocyte elastase				J Med Chem 33: 464-79 (1990) Checked by Author BindingDB Entry DOI: 10.7270/Q2PR7X6X
					More data for this Ligand-Target Pair