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SMILES: CCOc1nc2cc(N)ccc2c(=O)o1

InChI Key: InChIKey=IDPFNMHCMKYVDO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406290   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50406290
PNG
(CHEMBL141707)
Show SMILES CCOc1nc2cc(N)ccc2c(=O)o1
Show InChI InChI=1S/C10H10N2O3/c1-2-14-10-12-8-5-6(11)3-4-7(8)9(13)15-10/h3-5H,2,11H2,1H3
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Similars
PubMed
 6.31n/an/an/an/a 0.0000436 7.59E+3n/an/a



Syntex Research

Curated by ChEMBL


Assay Description
Component deacylation rate constant for interaction with human leukocyte elastase

J Med Chem 33: 464-79 (1990)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2PR7X6X
More data for this
Ligand-Target Pair