BDBM50406612 CHEMBL94800

SMILES: Cc1c(nc(C2CC2)c(COP([O-])(=O)C[C@H](O)CC([O-])=O)c1-c1ccc(F)cc1)-c1ccccc1

InChI Key: InChIKey=OFGMIUAUIDYZAY-OAQYLSRUSA-L

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HMG-CoA reductase (Rattus norvegicus (rat))	BDBM50406612 (CHEMBL94800) Show SMILES Cc1c(nc(C2CC2)c(COP([O-])(=O)C[C@H](O)CC([O-])=O)c1-c1ccc(F)cc1)-c1ccccc1 Show InChI InChI=1S/C26H27FNO6P/c1-16-24(17-9-11-20(27)12-10-17)22(14-34-35(32,33)15-21(29)13-23(30)31)26(19-7-8-19)28-25(16)18-5-3-2-4-6-18/h2-6,9-12,19,21,29H,7-8,13-15H2,1H3,(H,30,31)(H,32,33)/p-2/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition of rat hepatic HMG-CoA reductase.				J Med Chem 34: 2804-15 (1991) BindingDB Entry DOI: 10.7270/Q2H1336P
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