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SMILES: NC(=O)c1nc2ccccc2nc1Nc1cccc(c1)N1CCOCC1

InChI Key: InChIKey=ZJKZJUARZUHCNR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406887   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50406887
PNG
(CHEMBL4162709)
Show SMILES NC(=O)c1nc2ccccc2nc1Nc1cccc(c1)N1CCOCC1
Show InChI InChI=1S/C19H19N5O2/c20-18(25)17-19(23-16-7-2-1-6-15(16)22-17)21-13-4-3-5-14(12-13)24-8-10-26-11-9-24/h1-7,12H,8-11H2,(H2,20,25)(H,21,23)
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Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Tours

Curated by ChEMBL


Assay Description
Inhibition of recombinant human Pim1 expressed in bacterial expression system using histone H1 as substrate after 30 mins by ADP-Glo reagent based lu...

Eur J Med Chem 154: 101-109 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.056
BindingDB Entry DOI: 10.7270/Q2HM5C0X
More data for this
Ligand-Target Pair