BDBM50406892 CHEMBL4159749

SMILES: [K;v0+].[#7]-c1ccc(-[#7]-c2nc3ccccc3nc2-[#6](-[#8-])=O)cc1

InChI Key: InChIKey=WMTANWYOORGJPC-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50406892 (CHEMBL4159749) Show SMILES [K;v0+].[#7]-c1ccc(-[#7]-c2nc3ccccc3nc2-[#6](-[#8-])=O)cc1 Show InChI InChI=1S/C15H12N4O2/c16-9-5-7-10(8-6-9)17-14-13(15(20)21)18-11-3-1-2-4-12(11)19-14/h1-8H,16H2,(H,17,19)(H,20,21)/p-1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tours Curated by ChEMBL					Assay Description Inhibition of recombinant human Pim1 expressed in bacterial expression system using histone H1 as substrate after 30 mins by ADP-Glo reagent based lu...				Eur J Med Chem 154: 101-109 (2018) Article DOI: 10.1016/j.ejmech.2018.04.056 BindingDB Entry DOI: 10.7270/Q2HM5C0X
					More data for this Ligand-Target Pair