BDBM50407405 CHEMBL2115222
SMILES: C[C@]12CC[C@H]3[C@@H](CN=C4C(Cl)C(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Nc1c(cccc1C(F)(F)F)C(F)(F)F
InChI Key: InChIKey=PLXLNNOTMDSATC-DKYJKYDSSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50407405 (CHEMBL2115222) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Inc. Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I | J Med Chem 38: 2621-7 (1995) BindingDB Entry DOI: 10.7270/Q2C829XC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50407405 (CHEMBL2115222) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Inc. Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I | J Med Chem 38: 2621-7 (1995) BindingDB Entry DOI: 10.7270/Q2C829XC | |||||||||||
More data for this Ligand-Target Pair |