BDBM50407748 CHEMBL2114190

SMILES: CN(O)C(=O)Cc1ccc2OCc3ccccc3C(=O)c2c1

InChI Key: InChIKey=SMKZBAGZXFNCFF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50407748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50407748 (CHEMBL2114190) Show SMILES CN(O)C(=O)Cc1ccc2OCc3ccccc3C(=O)c2c1 Show InChI InChI=1S/C17H15NO4/c1-18(21)16(19)9-11-6-7-15-14(8-11)17(20)13-5-3-2-4-12(13)10-22-15/h2-8,21H,9-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant				J Med Chem 39: 246-52 (1996) Article DOI: 10.1021/jm950563z BindingDB Entry DOI: 10.7270/Q22806PF
					More data for this Ligand-Target Pair